3-Methylisoxazole-4-carboxylic acid

3-Methylisoxazole-4-carboxylic acid - Names and Identifiers

Name	3-Methylisoxazole-4-carboxylic acid
Synonyms	AKOS PAO-1630 Leflunomide Impurity 6 3-Methyl-4-isoxazolecarboxylic acid 3-Methylisoxazole-4-carboxylic acid 3-METHYLISOXAZOLE-4-CARBOXYLIC ACID 3-METHYL-4-ISOXAZOLECARBOXYLIC ACID 3-Methyl-1,2-oxazole-4-carboxylic acid 3-Methyl-4-Isoxazolecarboxylic Acid(WX614141) 3-Methyl-1,2-oxazole-4-carboxylic acid, 4-Carboxy-3-methylisoxazole
CAS	17153-20-7
EINECS	681-430-1
InChI	InChI=1/C5H5NO3/c1-3-4(5(7)8)2-9-6-3/h2H,1H3,(H,7,8)

3-Methylisoxazole-4-carboxylic acid - Physico-chemical Properties

Molecular Formula	C5H5NO3
Molar Mass	127.1
Density	1.348±0.06 g/cm3(Predicted)
Melting Point	185-187°C
Boling Point	303.6±22.0 °C(Predicted)
Flash Point	137.4°C
Solubility	DMSO (Slightly)
Vapor Presure	0.000404mmHg at 25°C
Appearance	White solid
Color	Brown
BRN	114157
pKa	2.90±0.25(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.514
MDL	MFCD01318161
Physical and Chemical Properties	Off-white solid

3-Methylisoxazole-4-carboxylic acid - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S22 - Do not breathe dust.
Hazard Note	Irritant

3-Methylisoxazole-4-carboxylic acid - Introduction

acid (acid) is an organic compound. The following is its nature, use, preparation and safety information:

Nature:
-Appearance: acid is a colorless crystalline solid;
-Solubility: Soluble in organic solvents, such as methanol, ethanol and chloroform;
-Melting Point: 140-142 ℃.

Use:
-Chemical intermediate: acid can be used as an intermediate for the synthesis of drugs and other organic compounds in the pharmaceutical field, and is used to synthesize various biologically active compounds;
-Anti-tumor drug research: The compound can be used to research and develop new anti-tumor drugs.

Method:
The preparation method of acid usually includes the following steps:
1. Take 3-methyliso-oxazole as the starting material;
2. React in an appropriate solvent, such as acetic acid or acetone, the reaction time and temperature depend on the specific reaction conditions;
3. The target product is obtained by crystallization or other separation techniques.

Safety Information:
The safety information of acid is currently insufficient. Therefore, appropriate safety measures need to be taken during handling and use, such as wearing protective gloves, goggles and suitable work clothes. In the laboratory, it is necessary to follow the corresponding operating procedures to ensure the safety of personnel. In addition, the compound may be harmful to the environment, so take appropriate measures to comply with relevant laws and regulations when handling and disposing of waste.

Last Update：2024-04-09 20:49:11